Unlocking the secret to skin longevity: The power of the proteome
Ageing is a natural process, but what if we could better understand and support the very foundation of our skin’s longevity? Science now reveals that proteins—collectively known as the proteome—play a crucial role in maintaining the health, structure, and function of our skin. While water makes up the majority of our body’s composition, proteins are the second-largest component, essential for cellular repair, communication, and renewal
Science of skin ageing: Professor Radman’s groundbreaking discovery
The work of Professor Miroslav Radman, a renowned expert in cell longevity, has led to groundbreaking discoveries in the science of ageing. His research, inspired by extremophile bacteria such as Deinococcus radiodurans, reveals that ageing is influenced not just by DNA but also by proteins. These bacteria exhibit an extraordinary ability to repair themselves after extreme conditions, hinting at a new understanding of biological resilience and longevity.
A shared vision
Partnering with Jean-Noël Thorel, founder of NAOS, Professor Radman emphasises that skin health plays a vital role in longevity. Their research led to a shift from a DNA-centric to a protein-centric view of ageing, as proteins are crucial for cellular repair and the key to longevity. This collaboration between NAOS ageing SCIENCE and Radman’s MedILS resulted in the development of Age Proteom™ Biotechnology; an extract of snow bacteria capable of regeneration under extreme conditions which boosts the skin's ability to repair itself and consequently halve the speed of natural ageing process.


Age Proteom – The cutting-edge formula to skin longevity
AGE PROTEOM™ ADVANCED SERUM is a revolutionary serum developed through over 40 years of scientific research by renowned cell longevity expert Professor Miroslav Radman and Institut Esthederm’s founder, pharmacist Jean-Noël Thorel. The formula is designed to protect and strengthen the skin’s proteome—the full set of proteins within each cell—slowing down the natural ageing process by 55% and addressing all signs of ageing.
At the heart of the serum is AGE PROTEOM™ ADVANCED BIOTECHNOLOGY, featuring a unique snow bacteria extract. This remarkable microorganism, known for its resilience in extreme conditions, provides powerful antioxidant protection. It shields essential proteins like DNA-repairing enzymes, collagen, and elastin from environmental stressors, including UV exposure, cold, and oxidative damage. The result is a visibly younger-looking complexion with smoother skin texture and wrinkles, improved tone, and enhanced radiance.